SNX17 抗体 (N-Term)
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- 抗原 See all SNX17 抗体
- SNX17 (Sorting Nexin 17 (SNX17))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNX17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- SNX17 Antibody detects endogenous levels of total SNX17.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SNX17, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SNX17 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SNX17 (Sorting Nexin 17 (SNX17))
- 别名
- SNX17 (SNX17 产品)
- 别名
- snx17 antibody, MGC53167 antibody, MGC69341 antibody, MGC198061 antibody, MGC83142 antibody, SNX17 antibody, wu:fb67g03 antibody, wu:fb67g09 antibody, wu:fc27g08 antibody, wu:fj81d04 antibody, si:ch211-101l18.2 antibody, 5830447M19Rik antibody, AI790646 antibody, D5Ertd260e antibody, mKIAA0064 antibody, sorting nexin 17 antibody, sorting nexin 17 L homeolog antibody, snx17 antibody, SNX17 antibody, snx17.L antibody, Snx17 antibody
- 背景
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Description: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)).
Gene: SNX17
- 分子量
- 50 kDa
- 基因ID
- 9784
- UniProt
- Q15036
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