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- 抗原 See all SNAPIN 抗体
- SNAPIN (SNAP-Associated Protein (SNAPIN))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SNAPIN antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- SNAPIN Antibody detects endogenous levels of total SNAPIN.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SNAPIN, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SNAPIN Primary Antibody
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anti-SNAP-Associated Protein (SNAPIN) (AA 41-136) antibody
SNAPIN 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 1-136) antibodySNAPIN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 2-136) antibodySNAPIN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 41-136) antibodySNAPIN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 1-136) antibodySNAPIN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SNAP-Associated Protein (SNAPIN) (AA 117-136), (C-Term) antibodySNAPIN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SNAPIN (SNAP-Associated Protein (SNAPIN))
- 别名
- SNAPIN (SNAPIN 产品)
- 别名
- SNAPAP antibody, si:dkey-222b8.2 antibody, SNAPIN antibody, BLOC1S7 antibody, BLOS7 antibody, 25kDa antibody, AA407989 antibody, AV026596 antibody, Bloc1s7 antibody, Snap25bp antibody, Snapap antibody, SNAP associated protein antibody, SNAP-associated protein L homeolog antibody, SNAP-associated protein antibody, SNAPIN antibody, snapin.L antibody, snapin antibody, Snapin antibody
- 背景
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Description: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells (PubMed:17182842, PubMed:18167355). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).
Gene: SNAPIN
- 分子量
- 15-18 kDa
- 基因ID
- 23557
- UniProt
- O95295
- 途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
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