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SMCR7L 抗体 (Internal Region)

SMCR7L 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265187
发货至: 中国
  • 抗原 See all SMCR7L 抗体
    SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 6
    • 1
    • 1
    Internal Region
    适用
    • 27
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    克隆类型
    • 40
    多克隆
    标记
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMCR7L antibody is un-conjugated
    应用范围
    • 36
    • 22
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    SMCR7L/MID51 Antibody detects endogenous levels of total SMCR7L/MID51.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human SMCR7L/MID51, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product SMCR7L Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))
    别名
    MIEF1 (SMCR7L 产品)
    别名
    MGC115280 antibody, HSU79252 antibody, MID51 antibody, MIEF1 antibody, dJ1104E15.3 antibody, A230016E22 antibody, AI452372 antibody, im:7156228 antibody, smcr7l antibody, zgc:162279 antibody, mitochondrial elongation factor 1 antibody, mitochondrial elongation factor 1 S homeolog antibody, MIEF1 antibody, mief1.S antibody, Mief1 antibody, mief1 antibody
    背景

    Description: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.

    Gene: MIEF1

    分子量
    48-51 kDa
    基因ID
    54471
    UniProt
    Q9NQG6
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