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- 抗原 See all SMAD7 抗体
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMAD7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- Smad7 Antibody detects endogenous levels of total Smad7.
- 预测反应
- Pig,Bovine,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Smad7, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SMAD7 Primary Antibody
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anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 1-100) antibody
SMAD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E9 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 302-400) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 36-247) antibodySMAD7 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 195-224) antibodySMAD7 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18598 unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 160-260) antibodySMAD7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SMAD, Mothers Against DPP Homolog 7 (SMAD7) (AA 24-73) antibodySMAD7 适用: 人, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- 别名
- SMAD7 (SMAD7 产品)
- 别名
- CRCS3 antibody, MADH7 antibody, MADH8 antibody, Smad7a antibody, Madh7 antibody, Smad10 antibody, madh7 antibody, xsmad7 antibody, wu:fj60c10 antibody, SMAD family member 7 antibody, SMAD family member 7 L homeolog antibody, SMAD7 antibody, Smad7 antibody, smad7.L antibody, smad7 antibody
- 背景
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Description: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A-PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Gene: SMAD7
- 分子量
- 46 kDa
- 基因ID
- 4092
- UniProt
- O15105
- 途径
- Interferon-gamma Pathway, Cell-Cell Junction Organization
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