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SKP1 抗体 (Internal Region)

Name: SKP1 抗体 (Internal Region)
SKU: ABIN6265102
Availability: OutOfStock

SKP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of Hela whole cell lysates, using SKP1 Antibody. (SKP1 抗体 (Internal Region))

Western blot analysis of extracts from 293, using SKP1 Antibody. (SKP1 抗体 (Internal Region))

IF/ICC

ABIN6277278 at 1/100 staining Rat brain tissue by IHC-P. (SKP1 抗体 (Internal Region))

IHC

4 images

产品编号 ABIN6265102

发货至: 中国

Datasheet as PDF

抗原 See all SKP1 抗体

SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))
抗原表位
15

7

7

6

4

3

2

1

1

1

1

1

1

1

1
Internal Region
适用
48

38

37

4

2

2

2

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
58

5
兔
Compatible Secondaries
克隆类型
51

12
多克隆
标记
26

5

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This SKP1 antibody is un-conjugated
应用范围
43

24

14

13

9

8

3

2

2

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

Skp1 Antibody detects endogenous levels of total Skp1.

预测反应

Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human Skp1, corresponding to a region within the internal amino acids.

亚型

IgG

Top Product

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anti-S-Phase Kinase-Associated Protein 1 (SKP1) antibody
SKP1 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4E11 unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 53-160) antibody
SKP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H8 unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) antibody
SKP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibody
SKP1 适用: 人, 大鼠, 猴, 小鸡, Cow, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) antibody
SKP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibody
SKP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-160) antibody
SKP1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 81-163) antibody
SKP1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 2-163) antibody
SKP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-S-Phase Kinase-Associated Protein 1 (SKP1) (AA 1-163) antibody
SKP1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

别名

SKP1 (SKP1 产品)

别名

EMC19 antibody, OCP-II antibody, OCP2 antibody, SKP1A antibody, TCEB1L antibody, p19A antibody, 15kDa antibody, 2610043E24Rik antibody, 2610206H23Rik antibody, SKP1 antibody, Tceb1l antibody, p19Skp1 antibody, Skp1a antibody, skp1a antibody, zgc:73186 antibody, ocp2 antibody, emc19 antibody, ocp-ii antibody, tceb1l antibody, ARABIDOPSIS SKP1 HOMOLOGUE 1 antibody, ASK1 antibody, ATSKP1 antibody, S phase kinase-associated protein 1 antibody, T4O12.17 antibody, T4O12_17 antibody, UFO INTERACTING PROTEIN 1 antibody, UIP1 antibody, ocp-2 antibody, S-phase kinase associated protein 1 antibody, S-phase kinase-associated protein 1 antibody, S-phase kinase-associated protein 1 pseudogene antibody, S-phase kinase-associated protein 1A antibody, S-phase kinase-associated protein 1 S homeolog antibody, S phase kinase-associated protein 1 antibody, SKP1 antibody, skp1 antibody, LOC100340043 antibody, Skp1a antibody, Skp1 antibody, skp1.S antibody

背景

Description: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2 (PubMed:25704143). SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1. SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. SCF(FBXW2) directs ubiquitination of GCM1. SCF(FBXO32) directs ubiquitination of MYOD1. SCF(FBXO7) directs ubiquitination of BIRC2 and DLGAP5. SCF(FBXO33) directs ubiquitination of YBX1. SCF(FBXO11) directs ubiquitination of BCL6 and DTL but does not seem to direct ubiquitination of TP53. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22', the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(CCNF) directs ubiquitination of CCP110. SCF(FBXL3) and SCF(FBXL21) direct ubiquitination of CRY1 and CRY2. SCF(FBXO9) directs ubiquitination of TTI1 and TELO2. SCF(FBXO10) directs ubiquitination of BCL2.
Gene: SKP1

分子量

18kDa

基因ID

6500

UniProt

P63208

途径

Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases