SENP6 抗体 (Internal Region)
Quick Overview for SENP6 抗体 (Internal Region) (ABIN6264987)
抗原
See all SENP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- SENP6 Antibody detects endogenous levels of total SENP6.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SENP6, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1-110) antibody
SENP6 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 4B7 unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (Internal Region) antibodyVerified SENP6 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1081-1112), (C-Term) antibodySENP6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0664 unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) antibodySENP6 适用: 人 ELISA, IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (C-Term) antibodySENP6 适用: 人, Cow, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) antibodySENP6 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 1-270) antibodySENP6 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (C-Term) antibodySENP6 适用: 人, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (AA 811-1112) antibodySENP6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Protease 6 (SENP6) (C-Term) antibodySENP6 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:50-1:200, WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SENP6 (SUMO1/sentrin Specific Protease 6 (SENP6))
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别名
- SENP6
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背景
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Description: Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation. Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination.
Gene: SENP6
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分子量
- 126kDa
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基因ID
- 26054
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UniProt
- Q9GZR1
抗原
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