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SENP2 抗体

SENP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264984
发货至: 中国
  • 抗原 See all SENP2 抗体
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    适用
    • 38
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    人, 小鼠, 大鼠
    宿主
    • 47
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    克隆类型
    • 47
    • 7
    多克隆
    标记
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    This SENP2 antibody is un-conjugated
    应用范围
    • 44
    • 18
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    • 4
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    SENP2 Antibody detects endogenous levels of total SENP2
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human SENP2
    亚型
    IgG
    Top Product
    Discover our top product SENP2 Primary Antibody
  • 应用备注
    WB 1:1000-3000 IF/ICC 1:200-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
    别名
    SENP2 (SENP2 产品)
    别名
    2310007L05Rik antibody, 4930538C18Rik antibody, AI646780 antibody, AW554757 antibody, Smt3ip2 antibody, SuPr-1 antibody, mKIAA1331 antibody, AXAM2 antibody, SMT3IP2 antibody, Axam antibody, SUMO/sentrin specific peptidase 2 antibody, SUMO1/sentrin/SMT3 specific peptidase 2 antibody, Sumo1/sentrin/SMT3 specific peptidase 2 antibody, Senp2 antibody, SENP2 antibody
    背景

    Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).

    Gene: SENP2

    分子量
    68 kDa
    基因ID
    59343
    UniProt
    Q9HC62
    途径
    Chromatin Binding
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