RUNX3 抗体 (Internal Region)
(1 reference)-
- 抗原 See all RUNX3 抗体
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RUNX3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- RUNX3 Antibody detects endogenous levels of total RUNX3.
- 预测反应
- Pig,Bovine,Horse,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RUNX3, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RUNX3 Primary Antibody
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anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 31-130) antibody
RUNX3 适用: 人 WB, ELISA, IF (p), FACS, IF (cc), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 1-429) antibodyRUNX3 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 294-429) antibodyRUNX3 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 7E2B8 unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 128-270) antibodyRUNX3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 186-252) antibodyRUNX3 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 1-429) antibodyRUNX3 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 168-197) antibodyRUNX3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 1-415) antibodyRUNX3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 194-279) antibodyRUNX3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 3 (RUNX3) (AA 294-429) antibodyRUNX3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 8C9B6 unconjugated
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- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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: "MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway." in: Gene, Vol. 641, pp. 240-247, (2017) (PubMed).
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: "MiR-93-5p promotes gastric cancer-cell progression via inactivation of the Hippo signaling pathway." in: Gene, Vol. 641, pp. 240-247, (2017) (PubMed).
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- 抗原
- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
- 别名
- RUNX3 (RUNX3 产品)
- 别名
- runxb antibody, RUNX3 antibody, CBFA3 antibody, frrunx3 antibody, runx3 antibody, aml2 antibody, cbfa3 antibody, pebp2ac antibody, AML2 antibody, Cbfa3 antibody, Pebp2a3 antibody, PEBP2aC antibody, runt-related transcription factor 3 antibody, runt related transcription factor 3 antibody, runt related transcription factor 3 L homeolog antibody, runx3 antibody, RUNX3 antibody, runx3.L antibody, Runx3 antibody
- 背景
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Description: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters (By similarity). May be involved in the control of cellular proliferation and/or differentiation. In association with ZFHX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712). CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development. They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation. CBF complexes binding to the transcriptional silencer is essential for recruitment of nuclear protein complexes that catalyze epigenetic modifications to establish epigenetic ZBTB7B silencing (By similarity).
Gene: RUNX3
- 分子量
- 44 kDa
- 基因ID
- 864
- UniProt
- Q13761
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