RRAGA 抗体 (C-Term)
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- 抗原 See all RRAGA 抗体
- RRAGA (Ras-Related GTP Binding A (RRAGA))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RRAGA antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 特异性
- RRAGA Antibody detects endogenous levels of total RRAGA.
- 预测反应
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RRAGA, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RRAGA Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RRAGA (Ras-Related GTP Binding A (RRAGA))
- 别名
- RRAGA (RRAGA 产品)
- 别名
- FIP-1 antibody, FIP1 antibody, RAGA antibody, 1300010C19Rik antibody, AI255374 antibody, Raga antibody, Ras related GTP binding A antibody, Ras-related GTP binding A antibody, RRAGA antibody, Rraga antibody
- 背景
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Description: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death.
Gene: RRAGA
- 分子量
- 37 kDa
- 基因ID
- 10670
- UniProt
- Q7L523
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