RNF5 抗体 (C-Term)
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- 抗原 See all RNF5 抗体
- RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- RNF5 Antibody detects endogenous levels of total RNF5.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RNF5, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RNF5 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))
- 别名
- RNF5 (RNF5 产品)
- 别名
- 2410131O05Rik antibody, AA407576 antibody, NG2 antibody, RING5 antibody, RMA1 antibody, ring finger protein 5 antibody, Rnf5 antibody, RNF5 antibody
- 背景
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Description: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses.
Gene: RNF5
- 分子量
- 20 kDa
- 基因ID
- 6048
- UniProt
- Q99942
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