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RNF5 抗体 (C-Term)

RNF5 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264790
发货至: 中国
  • 抗原 See all RNF5 抗体
    RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))
    抗原表位
    • 11
    • 9
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 1
    C-Term
    适用
    • 47
    • 13
    • 12
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 47
    克隆类型
    • 47
    多克隆
    标记
    • 20
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF5 antibody is un-conjugated
    应用范围
    • 40
    • 27
    • 16
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    RNF5 Antibody detects endogenous levels of total RNF5.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RNF5, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product RNF5 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    RNF5 (Ring Finger Protein 5, E3 Ubiquitin Protein Ligase (RNF5))
    别名
    RNF5 (RNF5 产品)
    别名
    2410131O05Rik antibody, AA407576 antibody, NG2 antibody, RING5 antibody, RMA1 antibody, ring finger protein 5 antibody, Rnf5 antibody, RNF5 antibody
    背景

    Description: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugating enzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secreted protein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD, the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N. Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation, the ubiquitination occurs in mitochondria after viral transfection and regulates antiviral responses.

    Gene: RNF5

    分子量
    20 kDa
    基因ID
    6048
    UniProt
    Q99942
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