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ARHGAP24 抗体 (Internal Region)

ARHGAP24 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264735
发货至: 中国
  • 抗原 See all ARHGAP24 抗体
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    抗原表位
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    Internal Region
    适用
    • 27
    • 9
    • 9
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 25
    • 2
    克隆类型
    • 27
    多克隆
    标记
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGAP24 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    RHG24 Antibody detects endogenous levels of total RHG24.
    预测反应
    Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RHG24, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ARHGAP24 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))
    别名
    ARHGAP24 (ARHGAP24 产品)
    别名
    FILGAP antibody, RC-GAP72 antibody, RCGAP72 antibody, p73 antibody, p73RhoGAP antibody, 0610025G21Rik antibody, si:ch211-65i12.2 antibody, Rho GTPase activating protein 24 antibody, ARHGAP24 antibody, Arhgap24 antibody, arhgap24 antibody
    背景

    Description: Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

    Gene: ARHGAP24

    分子量
    84 kDa
    基因ID
    83478
    UniProt
    Q8N264
    途径
    Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
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