RGS17 抗体 (N-Term)
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- 抗原 See all RGS17 抗体
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RGS17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- RGS17 Antibody detects endogenous levels of total RGS17.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RGS17, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
- 别名
- RGS17 (RGS17 产品)
- 别名
- RGS17 antibody, zgc:92802 antibody, MGC179306 antibody, RGS-17 antibody, RGSZ2 antibody, hRGS17 antibody, 6430507P11Rik antibody, Rgsz2 antibody, regulator of G protein signaling 17 antibody, regulator of G-protein signaling 17 antibody, RGS17 antibody, Rgs17 antibody, rgs17 antibody
- 背景
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Description: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:15096504). Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).
Gene: RGS17
- 分子量
- 24 kDa
- 基因ID
- 26575
- UniProt
- Q9UGC6
- 途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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