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- 抗原 See all REST 抗体
- REST (RE1-Silencing Transcription Factor (REST))
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抗原表位
- C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This REST antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- REST Antibody detects endogenous levels of total REST.
- 预测反应
- Horse,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human REST, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product REST Primary Antibody
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anti-RE1-Silencing Transcription Factor (REST) (AA 401-450) antibody
REST 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (Middle Region) antibodyREST 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) antibodyREST 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 760-1060) antibodyREST 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 250-350) antibodyREST 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 20-69) antibodyREST 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (Internal Region) antibodyVerified REST 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 972-1021) antibodyREST 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 542-570) antibodyREST 适用: 人 WB 宿主: 兔 Polyclonal RB36730 unconjugated
anti-RE1-Silencing Transcription Factor (REST) (AA 542-570) antibodyREST 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- REST (RE1-Silencing Transcription Factor (REST))
- 别名
- REST (REST 产品)
- 别名
- NRSF antibody, XBR antibody, 2610008J04Rik antibody, AA407358 antibody, xbr antibody, nrsf antibody, rest antibody, resta antibody, REST antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, RE1-silencing transcription factor S homeolog antibody, REST antibody, Rest antibody, rest.S antibody, rest antibody, LOC615792 antibody
- 背景
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Description: Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.
Gene: REST
- 分子量
- 121 kDa
- 基因ID
- 5978
- UniProt
- Q13127
- 途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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