RCC1 抗体 (N-Term)
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- 抗原 See all RCC1 抗体
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RCC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- RCC1 Antibody detects endogenous levels of total RCC1.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RCC1, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RCC1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
- 别名
- RCC1 (RCC1 产品)
- 别名
- Chc1 antibody, zgc:65796 antibody, zgc:77114 antibody, wu:fj77f08 antibody, rcc1 antibody, chc1-a antibody, BJ1 antibody, CG10480 antibody, CG18640 (Bj1) antibody, Dmel\\CG10480 antibody, RCC1 antibody, RanGEF antibody, Rcc1 antibody, dRCC1 antibody, inxs antibody, sdt antibody, xrcc1 antibody, chc1-b antibody, MGC115703 antibody, MGC132085 antibody, CHC1 antibody, RCC1-I antibody, SNHG3-RCC1 antibody, 4931417M11Rik antibody, AI326872 antibody, regulator of chromosome condensation 1 antibody, regulator of chromosome condensation 1 L homeolog antibody, Regulator of chromosome condensation 1 antibody, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted antibody, regulator of chromosome condensation 1 S homeolog antibody, rcc1 antibody, RCC1 antibody, rcc1.L antibody, Rcc1 antibody, rcc1.S antibody
- 背景
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Description: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).
Gene: RCC1
- 分子量
- ?45 kDa
- 基因ID
- 1104
- UniProt
- P18754
- 途径
- Chromatin Binding, Protein targeting to Nucleus
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