RBM4 抗体 (Internal Region)
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- 抗原 See all RBM4 抗体
- RBM4 (RNA Binding Motif Protein 4 (RBM4))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBM4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- RBM4 Antibody detects endogenous levels of total RBM4.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RBM4, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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anti-RNA Binding Motif Protein 4 (RBM4) (AA 121-205) antibody
RBM4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) antibodyRBM4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) (AA 177-207) antibodyRBM4 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) (AA 152-201) antibodyRBM4 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-RNA Binding Motif Protein 4 (RBM4) (Middle Region) antibodyRBM4 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, Cow, 犬, 山羊 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- RBM4 (RNA Binding Motif Protein 4 (RBM4))
- 别名
- RBM4 (RBM4 产品)
- 别名
- rbm4 antibody, rna-bp4 antibody, wu:fc31f07 antibody, wu:fc57h11 antibody, zgc:56302 antibody, LARK antibody, RBM4A antibody, ZCCHC21 antibody, ZCRB3A antibody, 4921506I22Rik antibody, Lark1 antibody, Mlark antibody, Rbm4a antibody, lark antibody, Rbm4 antibody, RNA binding motif protein 4.1 antibody, RNA binding motif protein 4 antibody, RNA-binding protein 14 antibody, RNA-binding protein lark antibody, rbm4.1 antibody, RBM4 antibody, LOC610648 antibody, Rbm4 antibody, LARK antibody
- 背景
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Description: RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro.
Gene: RBM4
- 分子量
- 40 kDa
- 基因ID
- 5936
- UniProt
- Q9BWF3
- 途径
- Regulation of Muscle Cell Differentiation, Photoperiodism
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