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rala 抗体 (C-Term)

rala 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264624
发货至: 中国
  • 抗原 See all rala 抗体
    rala (Ras-related Protein Ral-A (rala))
    抗原表位
    • 13
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    • 1
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    C-Term
    适用
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    宿主
    • 43
    • 7
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    克隆类型
    • 45
    • 9
    多克隆
    标记
    • 31
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    This rala antibody is un-conjugated
    应用范围
    • 38
    • 26
    • 10
    • 5
    • 2
    • 2
    • 2
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    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    RALA Antibody detects endogenous levels of total RALA.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human RALA, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product rala Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    rala (Ras-related Protein Ral-A (rala))
    别名
    RALA (rala 产品)
    别名
    3010001O15Rik antibody, AW322615 antibody, Ral antibody, Rasl1 antibody, RAL antibody, v-ral simian leukemia viral oncogene A (ras related) antibody, RAS like proto-oncogene A antibody, Rala antibody, RALA antibody
    背景

    Description: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling (PubMed:20005108). Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells (PubMed:19306925). During mitosis, supports the stabilization and elongation of the intracellular bridge between dividing cells. Cooperates with EXOC2 to recruit other components of the exocyst to the early midbody (PubMed:18756269).

    Gene: RALA

    分子量
    24 kDa
    基因ID
    5898
    UniProt
    P11233
    途径
    Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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