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PSME3 抗体 (N-Term)

PSME3 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264495
发货至: 中国
  • 抗原 See all PSME3 抗体
    PSME3
    抗原表位
    • 5
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    • 4
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    • 1
    • 1
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    • 1
    N-Term
    适用
    • 46
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    • 5
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    • 4
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    • 2
    • 2
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    • 1
    人, 大鼠, 小鼠
    宿主
    • 42
    • 7
    克隆类型
    • 44
    • 5
    多克隆
    标记
    • 31
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
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    • 1
    This PSME3 antibody is un-conjugated
    应用范围
    • 35
    • 17
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    • 8
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    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    PSME3 Antibody detects endogenous levels of total PSME3.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PSME3, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PSME3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PSME3
    别名
    PSME3 (PSME3 产品)
    别名
    AA410043 antibody, AU020960 antibody, Ki antibody, PA28gamma antibody, REGgamma antibody, pa28g antibody, Ab2-371 antibody, PA28-gamma antibody, PA28G antibody, REG-GAMMA antibody, psme3b antibody, proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki) antibody, proteasome activator subunit 3 antibody, proteasome activator subunit 3 S homeolog antibody, Psme3 antibody, PSME3 antibody, psme3.S antibody
    背景

    Description: Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).

    Gene: PSME3

    分子量
    30kDa
    基因ID
    10197
    UniProt
    P61289
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Hepatitis C, Synthesis of DNA
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