PRMT7 抗体 (Internal Region)
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- 抗原 See all PRMT7 抗体
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRMT7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- PRMT7 Antibody detects endogenous levels of total PRMT7.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PRMT7, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PRMT7 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))
- 别名
- PRMT7 (PRMT7 产品)
- 别名
- ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 7 antibody, ATPRMT7 antibody, DL4310W antibody, FCAALL.195 antibody, protein arginine methyltransferase 7 antibody, RGD1304869 antibody, 4933402B05Rik antibody, BC006705 antibody, zgc:66172 antibody, protein arginine methyltransferase 7 antibody, protein arginine methyltransferase 7 L homeolog antibody, protein arginine N-methyltransferase 7 antibody, Protein arginine N-methyltransferase 7 antibody, PRMT7 antibody, Prmt7 antibody, prmt7.L antibody, prmt7 antibody, prmt-7 antibody
- 背景
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Description: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3), such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro, the relevance of such results is however unclear in vivo.
Gene: PRMT7
- 分子量
- 78 kDa
- 基因ID
- 54496
- UniProt
- Q9NVM4
- 途径
- Ribonucleoprotein Complex Subunit Organization
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