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PRC1 抗体 (Internal Region)

PRC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264405
发货至: 中国
  • 抗原 See all PRC1 抗体
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    抗原表位
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠
    宿主
    • 22
    • 3
    克隆类型
    • 22
    • 3
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PRC1 antibody is un-conjugated
    应用范围
    • 11
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    PRC1 Antibody detects endogenous levels of total PRC1.
    预测反应
    Pig,Horse,Sheep,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PRC1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PRC1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, IF/ICC, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))
    别名
    PRC1 (PRC1 产品)
    别名
    cb212 antibody, prc1 antibody, prc1l antibody, zgc:55982 antibody, zgc:86918 antibody, MGC68845 antibody, zgc:55664 antibody, ase1 antibody, ASE1 antibody, D7Ertd348e antibody, protein regulator of cytokinesis 1 antibody, protein regulator of cytokinesis 1a antibody, protein regulator of cytokinesis 1 S homeolog antibody, protein regulator of cytokinesis 1b antibody, PRC1 antibody, prc1a antibody, prc1.S antibody, prc1b antibody, CNC07120 antibody, prc1 antibody, Prc1 antibody
    背景

    Description: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436).

    Gene: PRC1

    分子量
    72kDa
    基因ID
    9055
    UniProt
    O43663
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