PPP4C 抗体 (C-Term)
Quick Overview for PPP4C 抗体 (C-Term) (ABIN6264398)
抗原
See all PPP4C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- PPP4C Antibody detects endogenous levels of total PPP4C.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PPP4C, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibody
PPP4C 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 265-307) antibodyPPP4C 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyVerified PPP4C 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyPPP4C 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 218-307) antibodyPPP4C 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyPPP4C 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 马, 豚鼠, 斑马鱼, Bat, Hamster, 猴, 非洲爪蟾, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 160-189) antibodyPPP4C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33771 unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))
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别名
- PPP4C
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背景
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Description: Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
Gene: PPP4C
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分子量
- 35kDa
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基因ID
- 5531
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UniProt
- P60510
抗原
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