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POLR3B 抗体 (C-Term)

POLR3B 适用: 人, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264349
发货至: 中国
  • 抗原 See all POLR3B 抗体
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    抗原表位
    • 7
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
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    • 27
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    • 3
    • 2
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    • 1
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    • 1
    人, 大鼠
    宿主
    • 37
    • 2
    克隆类型
    • 37
    • 2
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
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    • 2
    • 1
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    This POLR3B antibody is un-conjugated
    应用范围
    • 27
    • 23
    • 4
    • 2
    • 2
    • 1
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    POLR3B Antibody detects endogenous levels of total POLR3B.
    预测反应
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human POLR3B, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product POLR3B Primary Antibody
  • 应用备注
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    别名
    POLR3B (POLR3B 产品)
    别名
    RGD1565311 antibody, C128 antibody, HLD8 antibody, RPC2 antibody, 2700078H01Rik antibody, A330032P03Rik antibody, C85372 antibody, RNA polymerase III subunit B antibody, polymerase (RNA) III (DNA directed) polypeptide B antibody, Polr3b antibody, POLR3B antibody
    背景

    Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

    Gene: POLR3B

    分子量
    128kDa
    基因ID
    55703
    UniProt
    Q9NW08
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