POLR2D 抗体 (N-Term)
-
- 抗原 See all POLR2D 抗体
- POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
-
抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This POLR2D antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- POLR2D Antibody detects endogenous levels of total POLR2D.
- 预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human POLR2D, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product POLR2D Primary Antibody
-
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))
- 别名
- POLR2D (POLR2D 产品)
- 别名
- wu:fa95b11 antibody, zgc:110435 antibody, HSRBP4 antibody, HSRPB4 antibody, RBP4 antibody, RPB16 antibody, 2310002G05Rik antibody, 2610028L19Rik antibody, RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, polymerase (RNA) II (DNA directed) polypeptide D antibody, Polr2d antibody, CpipJ_CPIJ006734 antibody, UREG_01395 antibody, LOC100282338 antibody, polr2d antibody, POLR2D antibody
- 背景
-
Description: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity).
Gene: POLR2D
- 分子量
- 16kDa
- 基因ID
- 5433
- UniProt
- O15514
- 途径
- Regulatory RNA Pathways
-