PLA2G2A 抗体 (Internal Region)
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- 抗原 See all PLA2G2A 抗体
- PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
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抗原表位
- Internal Region
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLA2G2A antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- PLA2G2A Antibody detects endogenous levels of total PLA2G2A.
- 预测反应
- Pig,Horse,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PLA2G2A, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PLA2G2A Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PLA2G2A (Phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A))
- 别名
- PLA2G2A (PLA2G2A 产品)
- 别名
- MOM1 antibody, PLA2 antibody, PLA2B antibody, PLA2L antibody, PLA2S antibody, PLAS1 antibody, sPLA2 antibody, EF antibody, Mom1 antibody, Pla2 antibody, sPla2-IIA antibody, phospholipase A2 group IIA antibody, phospholipase A2, group IIA (platelets, synovial fluid) antibody, PLA2G2A antibody, Pla2g2a antibody
- 背景
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Description: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).
Gene: PLA2G2A
- 分子量
- 16kDa
- 基因ID
- 5320
- UniProt
- P14555
- 途径
- Stem Cell Maintenance, Inositol Metabolic Process
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