PIK3R6 抗体 (C-Term)
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- 抗原 See all PIK3R6 抗体
- PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PIK3R6 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 特异性
- PIK3R6 Antibody detects endogenous levels of total PIK3R6.
- 预测反应
- Pig,Bovine,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PIK3R6, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PIK3R6 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PIK3R6 (Phosphoinositide-3-Kinase, Regulatory Subunit 6 (PIK3R6))
- 别名
- PIK3R6 (PIK3R6 产品)
- 别名
- C17orf38 antibody, HsT41028 antibody, p84 antibody, p84 PIKAP antibody, p87(PIKAP) antibody, p87PIKAP antibody, BB220380 antibody, RGD1560850 antibody, phosphoinositide-3-kinase regulatory subunit 6 antibody, phosphoinositide-3-kinase regulatory subunit 5 antibody, phosphoinositide-3-kinase, regulatory subunit 6 antibody, PIK3R6 antibody, Pik3r6 antibody
- 背景
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Description: Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis, signaling seems to involve RRAS.
Gene: PIK3R6
- 分子量
- 84 kDa
- 基因ID
- 146850
- UniProt
- Q5UE93
- 途径
- PI3K-Akt Signaling, Inositol Metabolic Process
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