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PIF1 抗体 (Internal Region)

PIF1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264201
发货至: 中国
  • 抗原 See all PIF1 抗体
    PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
    抗原表位
    • 5
    • 1
    Internal Region
    适用
    人, 小鼠, 大鼠
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIF1 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    PIF1 Antibody detects endogenous levels of total PIF1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PIF1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PIF1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
    别名
    PIF1 (PIF1 产品)
    别名
    C15orf20 antibody, PIF antibody, 4631410M14 antibody, AI449441 antibody, cb934 antibody, fe11d03 antibody, wu:fe11d03 antibody, zgc:56161 antibody, PIF1 5'-to-3' DNA helicase antibody, PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) antibody, PIF1 antibody, Pif1 antibody, pif1.L antibody, pif1 antibody
    背景

    Description: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.

    Gene: PIF1

    分子量
    70 kDa
    基因ID
    80119
    UniProt
    Q9H611
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