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- 抗原 See all ALIX (PDCD6IP) 抗体
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ALIX antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- PDCD6IP Antibody detects endogenous levels of total PDCD6IP.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PDCD6IP, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PDCD6IP Primary Antibody
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anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-239) antibody
PDCD6IP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-180) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 174-383) antibodyPDCD6IP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-110) antibodyPDCD6IP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 601-700) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人 WB, ELISA, FACS 宿主: 兔 Monoclonal 7E9 unconjugated Recombinant Antibody
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
- 别名
- PDCD6IP (PDCD6IP 产品)
- 背景
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Description: Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complexes (PubMed:14739459). The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed:17853893, PubMed:17556548). Adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis (PubMed:17853893, PubMed:17556548, PubMed:18641129). May play a role in the regulation of both apoptosis and cell proliferation. Regulates exosome biogenesis in concert with SDC1/4 and SDCBP (PubMed:22660413). By interacting with F-actin, PARD3 and TJP1 secures the proper assembly and positioning of actomyosin-tight junction complex at the apical sides of adjacent epithelial cells that defines a spatial membrane domain essential for the maintenance of epithelial cell polarity and barrier (By similarity).
Gene: PDCD6IP
- 分子量
- 96 kDa
- 基因ID
- 10015
- UniProt
- Q8WUM4
- 途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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