PAK7 抗体 (C-Term)
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- 抗原 See all PAK7 抗体
- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- PAK5 Antibody detects endogenous levels of total PAK5.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human PAK5, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PAK7 Primary Antibody
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- 应用备注
- WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
- 别名
- PAK5 (PAK7 产品)
- 别名
- PAK5 antibody, pak5 antibody, 2900083L08Rik antibody, 6430627N20 antibody, Pak5 antibody, PAK-5 antibody, PAK-7 antibody, p21 (RAC1) activated kinase 5 antibody, p21 (RAC1) activated kinase 5 L homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 7 antibody, p21 (RAC1) activated kinase 7 antibody, PAK5 antibody, pak5.L antibody, Pak7 antibody
- 背景
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Description: Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.
Gene: PAK5
- 分子量
- 75kDa
- 基因ID
- 57144
- UniProt
- Q9P286
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