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ORAI1 抗体 (C-Term)

ORAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263901
发货至: 中国
  • 抗原 See all ORAI1 抗体
    ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
    抗原表位
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 51
    • 23
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 47
    • 6
    • 1
    克隆类型
    • 48
    • 6
    多克隆
    标记
    • 28
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ORAI1 antibody is un-conjugated
    应用范围
    • 40
    • 28
    • 13
    • 9
    • 8
    • 8
    • 4
    • 4
    • 4
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    ORAI1 Antibody detects endogenous levels of total ORAI1.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ORAI1, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ORAI1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
    别名
    ORAI1 (ORAI1 产品)
    背景

    Description: Ca2+ release-activated Ca2+ (CRAC) channel subunit which mediates Ca2+ influx following depletion of intracellular Ca2+ stores and channel activation by the Ca2+ sensor, STIM1 (PubMed:16582901, PubMed:16645049, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:19249086, PubMed:23307288, PubMed:24351972, PubMed:24591628, PubMed:28219928). CRAC channels are the main pathway for Ca2+ influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901).

    Gene: ORAI1

    分子量
    50 kDa
    基因ID
    84876
    UniProt
    Q96D31
    途径
    TCR Signaling, BCR Signaling
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