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NEUROD1 抗体 (N-Term)

NEUROD1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263609
发货至: 中国
  • 抗原 See all NEUROD1 抗体
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    抗原表位
    • 22
    • 16
    • 9
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 76
    • 64
    • 56
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 87
    • 6
    克隆类型
    • 80
    • 13
    多克隆
    标记
    • 37
    • 6
    • 6
    • 5
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    This NEUROD1 antibody is un-conjugated
    应用范围
    • 70
    • 38
    • 26
    • 26
    • 15
    • 13
    • 13
    • 12
    • 7
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    NEUROD1 Antibody detects endogenous levels of total NEUROD1.
    预测反应
    Pig,Bovine,Horse,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human NEUROD1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product NEUROD1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    NEUROD1 (Neuronal Differentiation 1 (NEUROD1))
    别名
    NEUROD1 (NEUROD1 产品)
    别名
    BETA2 antibody, BHF-1 antibody, MODY6 antibody, NEUROD antibody, bHLHa3 antibody, Neurod antibody, neurod antibody, XNeuroD antibody, MGC82572 antibody, NEUROD1 antibody, ND1 antibody, beta2 antibody, bhf-1 antibody, neuro-D antibody, nrd antibody, neuroD antibody, neurod1 antibody, Beta2 antibody, neuronal differentiation 1 antibody, neurogenic differentiation 1 antibody, neuronal differentiation 1 S homeolog antibody, neuronal differentiation 1 L homeolog antibody, NEUROD1 antibody, Neurod1 antibody, neurod1.S antibody, neurod1 antibody, neurod1.L antibody
    背景

    Description: Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).

    Gene: NEUROD1

    分子量
    40kDa
    基因ID
    4760
    UniProt
    Q13562
    途径
    Dopaminergic Neurogenesis, Hormone Transport, Carbohydrate Homeostasis
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