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NEURL 抗体 (Internal Region)

Name: NEURL 抗体 (Internal Region)
SKU: ABIN6263606
Availability: OutOfStock

NEURL 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis Neuralized-1 using MCF7 whole cell lysates (NEURL 抗体 (Internal Region))

IF/ICC

2 images

产品编号 ABIN6263606

发货至: 中国

Datasheet as PDF

抗原 See all NEURL 抗体

NEURL (Neuralized Homolog (Drosophila) (NEURL))
抗原表位
15

11

11

9

8

7

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
62

38

38

3

2

2

2

2

2

1

1

1
人
宿主
73

4
兔
Compatible Secondaries
克隆类型
73

4
多克隆
标记
37

5

3

3

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This NEURL antibody is un-conjugated
应用范围
52

35

19

16

13

13

11

5

3

2

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

Neuralized-1 Antibody detects endogenous levels of total Neuralized-1.

预测反应

Pig,Bovine,Rabbit

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human Neuralized-1, corresponding to a region within the internal amino acids.

亚型

IgG

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anti-Neuralized Homolog (Drosophila) (NEURL) (Internal Region) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (Ser357) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1248) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (AA 158-186) antibody
NEURL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB21920 unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (Center) antibody
NEURL 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (Ser351) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (Ser352) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibody
NEURL 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr1221), (pTyr1222) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Neuralized Homolog (Drosophila) (NEURL) (pTyr877) antibody
NEURL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

NEURL (Neuralized Homolog (Drosophila) (NEURL))

别名

NEURL1 (NEURL 产品)

背景

Description: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor, inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.
Gene: NEURL1

分子量

62kDa

基因ID

9148

UniProt

O76050

途径

Notch Signaling, EGFR Signaling Pathway