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NEURL 抗体 (Internal Region)

NEURL 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263606
发货至: 中国
  • 抗原 See all NEURL 抗体
    NEURL (Neuralized Homolog (Drosophila) (NEURL))
    抗原表位
    • 15
    • 11
    • 11
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 75
    • 46
    • 46
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 86
    • 4
    克隆类型
    • 86
    • 4
    多克隆
    标记
    • 45
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    This NEURL antibody is un-conjugated
    应用范围
    • 62
    • 48
    • 26
    • 17
    • 14
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Neuralized-1 Antibody detects endogenous levels of total Neuralized-1.
    预测反应
    Pig,Bovine,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Neuralized-1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product NEURL Primary Antibody
  • 应用备注
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    NEURL (Neuralized Homolog (Drosophila) (NEURL))
    别名
    NEURL1 (NEURL 产品)
    别名
    Xneur antibody, neurl-A antibody, zgc:153971 antibody, si:dkey-82d4.1 antibody, si:dkey-82d4.3 antibody, h-neu antibody, rnf67 antibody, neurl1 antibody, neuralized antibody, NEURL1 antibody, RNF67 antibody, bA416N2.1 antibody, neu antibody, neu-1 antibody, 2410129E16Rik antibody, AI450910 antibody, AI481072 antibody, Neu1 antibody, Neur1 antibody, Neurl antibody, Nlz antibody, Rnf67 antibody, Neurl1a antibody, NEURL antibody, neurlb antibody, zgc:153175 antibody, neuralized E3 ubiquitin protein ligase 1 L homeolog antibody, neuralized E3 ubiquitin protein ligase 1 antibody, neuralized E3 ubiquitin protein ligase 1Aa antibody, neuralized E3 ubiquitin protein ligase 1A antibody, neuralized E3 ubiquitin protein ligase 1Ab antibody, neurl1.L antibody, NEURL1 antibody, neurl1aa antibody, neurl1 antibody, Neurl1a antibody, Neurl1 antibody, neurl1ab antibody
    背景

    Description: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor, inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.

    Gene: NEURL1

    分子量
    62kDa
    基因ID
    9148
    UniProt
    O76050
    途径
    Notch Signaling, EGFR Signaling Pathway
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