NEURL 抗体 (Internal Region)
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- 抗原 See all NEURL 抗体
- NEURL (Neuralized Homolog (Drosophila) (NEURL))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEURL antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Neuralized-1 Antibody detects endogenous levels of total Neuralized-1.
- 预测反应
- Pig,Bovine,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Neuralized-1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NEURL Primary Antibody
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- 应用备注
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NEURL (Neuralized Homolog (Drosophila) (NEURL))
- 别名
- NEURL1 (NEURL 产品)
- 别名
- Xneur antibody, neurl-A antibody, zgc:153971 antibody, si:dkey-82d4.1 antibody, si:dkey-82d4.3 antibody, h-neu antibody, rnf67 antibody, neurl1 antibody, neuralized antibody, NEURL1 antibody, RNF67 antibody, bA416N2.1 antibody, neu antibody, neu-1 antibody, 2410129E16Rik antibody, AI450910 antibody, AI481072 antibody, Neu1 antibody, Neur1 antibody, Neurl antibody, Nlz antibody, Rnf67 antibody, Neurl1a antibody, NEURL antibody, neurlb antibody, zgc:153175 antibody, neuralized E3 ubiquitin protein ligase 1 L homeolog antibody, neuralized E3 ubiquitin protein ligase 1 antibody, neuralized E3 ubiquitin protein ligase 1Aa antibody, neuralized E3 ubiquitin protein ligase 1A antibody, neuralized E3 ubiquitin protein ligase 1Ab antibody, neurl1.L antibody, NEURL1 antibody, neurl1aa antibody, neurl1 antibody, Neurl1a antibody, Neurl1 antibody, neurl1ab antibody
- 背景
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Description: Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor, inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway.
Gene: NEURL1
- 分子量
- 62kDa
- 基因ID
- 9148
- UniProt
- O76050
- 途径
- Notch Signaling, EGFR Signaling Pathway
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