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NDC80 抗体 (C-Term)

Name: NDC80 抗体 (C-Term)
SKU: ABIN6263548
Availability: OutOfStock

NDC80 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of K562 whole cell lysates, using NDC80 Antibody. (NDC80 抗体 (C-Term))

ABIN6277572 at 1/100 staining Human kidney tissue by IHC-P. (NDC80 抗体 (C-Term))

IHC

Western blot analysis of extracts from 3T3, using NDC80 Antibody. (NDC80 抗体 (C-Term))

IF/ICC

4 images

产品编号 ABIN6263548

发货至: 中国

Datasheet as PDF

抗原 See all NDC80 抗体

NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))
抗原表位
4

4

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
46

20

11

1

1

1

1
人, 小鼠, 大鼠
宿主
39

7

1
兔
Compatible Secondaries
克隆类型
41

6
多克隆
标记
30

3

2

2

2

2

2

2

1

1
This NDC80 antibody is un-conjugated
应用范围
27

17

10

8

7

4

2

2

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

NDC80 Antibody detects endogenous levels of total NDC80.

预测反应

Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human NDC80, corresponding to a region within C-terminal amino acids.

亚型

IgG

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anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (C-Term) antibody
Verified NDC80 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-NDC80 Kinetochore Complex Component Homolog (NDC80) antibody
NDC80 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2497C3a unconjugated

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NDC80 适用: 人 WB 宿主: 兔 Polyclonal RB53951 unconjugated

anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 508-539) antibody
NDC80 适用: 人 WB 宿主: 兔 Polyclonal RB55345 unconjugated

anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 1-642) antibody
NDC80 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 1-642) antibody
NDC80 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 343-642) antibody
NDC80 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-NDC80 Kinetochore Complex Component Homolog (NDC80) antibody
NDC80 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

anti-NDC80 Kinetochore Complex Component Homolog (NDC80) (AA 351-400) antibody
NDC80 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

NDC80 (NDC80 Kinetochore Complex Component Homolog (NDC80))

别名

NDC80 (NDC80 产品)

别名

CG9938 antibody, Dmel\\CG9938 antibody, Hec1 antibody, NDC80 antibody, dNdc80 antibody, dmNdc80 antibody, hec1 antibody, KNTC2 antibody, ndc10 antibody, tid3 antibody, 2610020P18Rik antibody, AV139730 antibody, HEC antibody, HEC1 antibody, Kntc2 antibody, kntc2l antibody, wu:fb52e02 antibody, zgc:111801 antibody, HsHec1 antibody, TID3 antibody, hsNDC80 antibody, kntc2 antibody, NDC80, kinetochore complex component antibody, CG9938 gene product from transcript CG9938-RA antibody, spindle pole body protein Ndc80 antibody, kinetochore protein Ndc80 antibody, NDC80 homolog, kinetochore complex component (S. cerevisiae) antibody, NDC80 kinetochore complex component antibody, NDC80 kinetochore complex component S homeolog antibody, NDC80 antibody, Ndc80 antibody, ndc80 antibody, ndc80.S antibody

背景

Description: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020). Plays a role in chromosome congression and is essential for the end-on attachment of the kinetochores to spindle microtubules (PubMed:25743205, PubMed:23891108).
Gene: NDC80

分子量

74kDa

基因ID

10403

UniProt

O14777

途径

Maintenance of Protein Location