Nicastrin 抗体 (C-Term)
-
- 抗原 See all Nicastrin (NCSTN) 抗体
- Nicastrin (NCSTN)
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Nicastrin antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- NCSTN Antibody detects endogenous levels of total NCSTN.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NCSTN, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NCSTN Primary Antibody
-
anti-Nicastrin (NCSTN) (AA 16-115) antibody
NCSTN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 429-669) antibodyNCSTN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 21-120) antibodyNCSTN 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 99-133) antibodyNCSTN 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB53031 unconjugated
anti-Nicastrin (NCSTN) (AA 1-689) antibodyNCSTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 16-115) antibodyNCSTN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-Nicastrin (NCSTN) (AA 420-655) antibodyNCSTN 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nicastrin (NCSTN) (AA 35-534) antibodyNCSTN 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nicastrin (NCSTN) (N-Term) antibodyNCSTN 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nicastrin (NCSTN) (C-Term) antibodyNCSTN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- Nicastrin (NCSTN)
- 别名
- NCSTN (NCSTN 产品)
- 背景
-
Description: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein) (PubMed:10993067, PubMed:12679784, PubMed:25043039, PubMed:26280335). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.
Gene: NCSTN
- 分子量
- 77kDa
- 基因ID
- 23385
- UniProt
- Q92542
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
-
