NAT10 抗体 (Internal Region)
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- 抗原 See all NAT10 抗体
- NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAT10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- NAT10 Antibody detects endogenous levels of total NAT10.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NAT10, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NAT10 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NAT10 (N-Acetyltransferase 10 (GCN5-Related) (NAT10))
- 别名
- NAT10 (NAT10 产品)
- 别名
- ALP antibody, NET43 antibody, AI429152 antibody, zgc:66119 antibody, DDBDRAFT_0190093 antibody, DDBDRAFT_0234062 antibody, DDB_0190093 antibody, DDB_0234062 antibody, RGD1306717 antibody, N-acetyltransferase 10 antibody, N-acetyltransferase 10 (GCN5-related) antibody, ribosome biogenesis ATPase (predicted) antibody, hypothetical protein antibody, N-acetyltransferase 10 (GCN5-related) L homeolog antibody, NAT10 antibody, Nat10 antibody, nat10 antibody, CC1G_12871 antibody, MCYG_05927 antibody, PITG_19671 antibody, MGYG_06040 antibody, SPAC20G8.09c antibody, nat10.L antibody
- 背景
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Description: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs (PubMed:25411247, PubMed:25653167). Catalyzes the formation of N4-acetylcytidine (ac4C) at position 1842 in 18S rRNA (PubMed:25411247). May also catalyze the formation of ac4C at position 1337 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis (PubMed:25411247, PubMed:25653167). Catalyzes the formation of ac4C in serine and leucine tRNAs (By similarity). Requires the tRNA-binding adapter protein THUMBD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation (PubMed:25653167). Can acetylate both histones and microtubules (PubMed:14592445, PubMed:17631499, PubMed:19303003). Histone acetylation may regulate transcription and mitotic chromosome de-condensation (PubMed:17631499). Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization (PubMed:14592445, PubMed:18082603). Acetylates alpha-tubulin, which may affect microtubule stability and cell division (PubMed:19303003).
Gene: NAT10
- 分子量
- 116 kDa
- 基因ID
- 55226
- UniProt
- Q9H0A0
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