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MYOC 抗体 (Internal Region)

MYOC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263485
发货至: 中国
  • 抗原 See all MYOC 抗体
    MYOC (Myocilin (MYOC))
    抗原表位
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 29
    • 14
    • 14
    • 6
    • 2
    人, 小鼠, 大鼠
    宿主
    • 25
    • 4
    克隆类型
    • 26
    • 3
    多克隆
    标记
    • 15
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYOC antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 9
    • 9
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    MYOC Antibody detects endogenous levels of total MYOC.
    预测反应
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MYOC, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MYOC Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MYOC (Myocilin (MYOC))
    别名
    MYOC (MYOC 产品)
    别名
    MYOC antibody, MGC136645 antibody, zgc:136645 antibody, AI957332 antibody, GLC1A antibody, TIGR antibody, GPOA antibody, JOAG antibody, JOAG1 antibody, myocilin antibody, Tigr antibody, myocilin antibody, MYOC antibody, myoc antibody, Myoc antibody
    背景

    Description: Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a dose-dependent manner through mitogen-activated protein kinase signaling. Mediates myelination in the peripheral nervous system through ERBB2/ERBB3 signaling. Plays a role as a regulator of muscle hypertrophy through the components of dystrophin-associated protein complex. Involved in positive regulation of mitochondrial depolarization. Plays a role in neurite outgrowth. May participate in the obstruction of fluid outflow in the trabecular meshwork.

    Gene: MYOC

    分子量
    57kDa
    基因ID
    4653
    UniProt
    Q99972
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