Myosin XVIIIA 抗体 (Internal Region)
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- 抗原 See all Myosin XVIIIA (MYO18A) 抗体
- Myosin XVIIIA (MYO18A)
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抗原表位
- Internal Region
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Myosin XVIIIA antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- MYO18A Antibody detects endogenous levels of total MYO18A.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human MYO18A, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- Myosin XVIIIA (MYO18A)
- 别名
- MYO18A (MYO18A 产品)
- 别名
- myosin-18 antibody, MYSPDZ antibody, SPR210 antibody, MyoPDZ antibody, MysPDZ antibody, myosin XVIIIa antibody, myosin XVIIIA antibody, unconventional myosin-XVIIIa antibody, myosin XVIIIA L homeolog antibody, Myosin XVIIIA antibody, myosin xviiia antibody, Myo18a antibody, MYO18A antibody, myo18a antibody, LOC100183025 antibody, myo18a.L antibody, LOC100640961 antibody, Bm1_54460 antibody, LOAG_04825 antibody
- 背景
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Description: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).
Gene: MYO18A
- 分子量
- 230 kDa,190 kDa
- 基因ID
- 399687
- UniProt
- Q92614
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