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Myosin XVIIIA 抗体 (Internal Region)

MYO18A 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263478
发货至: 中国
  • 抗原 See all Myosin XVIIIA (MYO18A) 抗体
    Myosin XVIIIA (MYO18A)
    抗原表位
    • 4
    • 2
    • 1
    • 1
    • 1
    Internal Region
    适用
    人, 大鼠, 小鼠
    宿主
    • 11
    克隆类型
    • 11
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    This Myosin XVIIIA antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    MYO18A Antibody detects endogenous levels of total MYO18A.
    预测反应
    Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MYO18A, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Myosin XVIIIA (MYO18A)
    别名
    MYO18A (MYO18A 产品)
    别名
    myosin-18 antibody, MYSPDZ antibody, SPR210 antibody, MyoPDZ antibody, MysPDZ antibody, myosin XVIIIa antibody, myosin XVIIIA antibody, unconventional myosin-XVIIIa antibody, myosin XVIIIA L homeolog antibody, Myosin XVIIIA antibody, myosin xviiia antibody, Myo18a antibody, MYO18A antibody, myo18a antibody, LOC100183025 antibody, myo18a.L antibody, LOC100640961 antibody, Bm1_54460 antibody, LOAG_04825 antibody
    背景

    Description: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).

    Gene: MYO18A

    分子量
    230 kDa,190 kDa
    基因ID
    399687
    UniProt
    Q92614
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