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CDC42BPB 抗体 (C-Term)

CDC42BPB 适用: 人 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263348
发货至: 中国
  • 抗原 See all CDC42BPB 抗体
    CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
    抗原表位
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 23
    • 11
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 19
    • 4
    克隆类型
    • 20
    • 3
    多克隆
    标记
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    This CDC42BPB antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    MRCKbeta Antibody detects endogenous levels of total MRCKbeta.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MRCKbeta, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CDC42BPB Primary Antibody
  • 应用备注
    WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
    别名
    CDC42BPB (CDC42BPB 产品)
    别名
    CDC42BPB antibody, wu:fb98c02 antibody, wu:fc48b05 antibody, wu:fc90d12 antibody, si:dkeyp-93h6.2 antibody, MRCKb antibody, MRCKB antibody, CDC42 binding protein kinase beta antibody, CDC42 binding protein kinase beta (DMPK-like) antibody, CDC42BPB antibody, cdc42bpb antibody, Cdc42bpb antibody
    背景

    Description: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (By similarity).

    Gene: CDC42BPB

    分子量
    194kDa
    基因ID
    9578
    UniProt
    Q9Y5S2
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