CDC42BPB 抗体 (C-Term)
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- 抗原 See all CDC42BPB 抗体
- CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC42BPB antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- MRCKbeta Antibody detects endogenous levels of total MRCKbeta.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human MRCKbeta, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CDC42BPB Primary Antibody
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- 应用备注
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CDC42BPB (CDC42 Binding Protein Kinase beta (DMPK-Like) (CDC42BPB))
- 别名
- CDC42BPB (CDC42BPB 产品)
- 别名
- CDC42BPB antibody, wu:fb98c02 antibody, wu:fc48b05 antibody, wu:fc90d12 antibody, si:dkeyp-93h6.2 antibody, MRCKb antibody, MRCKB antibody, CDC42 binding protein kinase beta antibody, CDC42 binding protein kinase beta (DMPK-like) antibody, CDC42BPB antibody, cdc42bpb antibody, Cdc42bpb antibody
- 背景
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Description: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715, PubMed:21949762). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates PPP1R12A (PubMed:21457715). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation (By similarity).
Gene: CDC42BPB
- 分子量
- 194kDa
- 基因ID
- 9578
- UniProt
- Q9Y5S2
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