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MLKL 抗体 (Internal Region)

MLKL 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263279
发货至: 中国
  • 抗原 See all MLKL 抗体
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    抗原表位
    • 11
    • 11
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 55
    • 39
    • 16
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 67
    • 7
    克隆类型
    • 60
    • 14
    多克隆
    标记
    • 32
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    This MLKL antibody is un-conjugated
    应用范围
    • 32
    • 28
    • 13
    • 10
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    MLKL Antibody detects endogenous levels of total MLKL.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MLKL, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MLKL Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • Fang, Cao, Wang, Ye, Shen, Li, Hu, Gao: "Alterations in necroptosis during ALDH2‑mediated protection against high glucose‑induced H9c2 cardiac cell injury." in: Molecular medicine reports, Vol. 18, Issue 3, pp. 2807-2815, (2018) (PubMed).

  • 抗原
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    别名
    MLKL (MLKL 产品)
    别名
    MLKL antibody, 9130019I15Rik antibody, mixed lineage kinase domain like pseudokinase antibody, mixed lineage kinase domain-like antibody, MLKL antibody, mlkl antibody, Mlkl antibody
    背景

    Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

    Gene: MLKL

    分子量
    54kDa
    基因ID
    197259
    UniProt
    Q8NB16
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