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MCM8 抗体 (C-Term)

MCM8 适用: 人, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263168
发货至: 中国
  • 抗原 See all MCM8 抗体
    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
    抗原表位
    • 8
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 40
    • 10
    • 9
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 大鼠
    宿主
    • 39
    • 1
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM8 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    MCM8 Antibody detects endogenous levels of total MCM8.
    预测反应
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MCM8, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MCM8 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))
    别名
    MCM8 (MCM8 产品)
    别名
    C20orf154 antibody, dJ967N21.5 antibody, 5730432L01Rik antibody, minichromosome maintenance 8 homologous recombination repair factor antibody, minichromosome maintenance 8 homologous recombination repair factor L homeolog antibody, MCM8 antibody, Mcm8 antibody, mcm8.L antibody
    背景

    Description: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G1 phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.

    Gene: MCM8

    分子量
    94 kDa
    基因ID
    84515
    UniProt
    Q9UJA3
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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