MCM5 抗体 (N-Term)
Quick Overview for MCM5 抗体 (N-Term) (ABIN6263163)
抗原
See all MCM5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- MCM5 Antibody detects endogenous levels of total MCM5.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MCM5, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl,sodium azide and glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))
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别名
- MCM5
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背景
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Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
Gene: MCM5
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分子量
- 90kDa
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基因ID
- 4174
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UniProt
- P33992
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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