MCM10 抗体 (C-Term)
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- 抗原 See all MCM10 抗体
- MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MCM10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- MCM10 Antibody detects endogenous levels of total MCM10.
- 预测反应
- Pig,Zebrafish,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human MCM10, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))
- 别名
- MCM10 (MCM10 产品)
- 背景
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Description: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability, acts as a direct target of transcriptional repression by ZBTB38 (PubMed:24726359).
Gene: MCM10
- 分子量
- 97-105 kDa
- 基因ID
- 55388
- UniProt
- Q7L590
- 途径
- Mitotic G1-G1/S Phases, DNA Replication
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