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MBNL1 抗体 (C-Term)

MBNL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263151
发货至: 中国
  • 抗原 See all MBNL1 抗体
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    抗原表位
    • 13
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 38
    • 6
    • 1
    克隆类型
    • 39
    • 6
    多克隆
    标记
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
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    This MBNL1 antibody is un-conjugated
    应用范围
    • 35
    • 24
    • 7
    • 7
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    MBNL1 Antibody detects endogenous levels of total MBNL1.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human MBNL1, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product MBNL1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    MBNL1 (Muscleblind-like Protein 1 (MBNL1))
    别名
    MBNL1 (MBNL1 产品)
    别名
    MBNL1 antibody, zgc:153954 antibody, Mbnl antibody, mKIAA0428 antibody, EXP antibody, EXP35 antibody, EXP40 antibody, EXP42 antibody, MBNL antibody, muscleblind like splicing regulator 1 antibody, muscleblind-like splicing regulator 1 antibody, muscleblind like splicing factor 1 antibody, MBNL1 antibody, mbnl1 antibody, Mbnl1 antibody
    背景

    Description: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.

    Gene: MBNL1

    分子量
    42 kDa
    基因ID
    4154
    UniProt
    Q9NR56
    途径
    Ribonucleoprotein Complex Subunit Organization
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