MBD1 抗体 (C-Term)
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- 抗原 See all MBD1 抗体
- MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- MBD1 Antibody detects endogenous levels of total MBD1.
- 预测反应
- Pig,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human MBD1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product MBD1 Primary Antibody
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anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 415-508) antibody
MBD1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 415-508) antibodyMBD1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F6 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 1-605) antibodyMBD1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 106-355) antibodyMBD1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 376-405), (C-Term) antibodyMBD1 适用: 人 WB 宿主: 兔 Polyclonal RB2371 unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 犬, 兔, Cow, 豚鼠, 马, 小鼠, 猴, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) antibodyMBD1 适用: 人, 大鼠, 犬, 兔, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (N-Term) antibodyMBD1 适用: 人 WB, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) (AA 1-605) antibodyMBD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 1 (MBD1) antibodyMBD1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-MBD1-1 unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
- 别名
- MBD1 (MBD1 产品)
- 别名
- CXXC3 antibody, PCM1 antibody, RFT antibody, Cxxc3 antibody, CCDC11 antibody, methyl-CpG binding domain protein 1 antibody, MBD1 antibody, Mbd1 antibody
- 背景
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Description: Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. Probably forms a complex with SETDB1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Isoform 1 and isoform 2 can also repress transcription from unmethylated promoters.
Gene: MBD1
- 分子量
- 67 kDa
- 基因ID
- 4152
- UniProt
- Q9UIS9
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