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MAG 抗体 (C-Term)

Name: MAG 抗体 (C-Term)
SKU: ABIN6263053
Availability: OutOfStock

MAG 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of MAG using COLO205 whole lysates. (MAG 抗体 (C-Term))

ABIN6277856 at 1/100 staining Human liver cancer tissue by IHC-P. (MAG 抗体 (C-Term))

IHC

2 images

产品编号 ABIN6263053

发货至: 中国

Datasheet as PDF

抗原 See all MAG 抗体

MAG (Myelin Associated Glycoprotein (MAG))
抗原表位
15

8

6

5

4

4

4

3

2

2

2

2

1

1

1

1

1
C-Term
适用
61

30

27

3

2

2

1

1

1

1

1

1

1
人, 小鼠
宿主
53

10
兔
Compatible Secondaries
克隆类型
54

9
多克隆
标记
30

5

4

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MAG antibody is un-conjugated
应用范围
54

29

13

13

12

11

9

3

3

3

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

MAG Antibody detects endogenous levels of total MAG.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human MAG, corresponding to a region within C-terminal amino acids.

亚型

IgG

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anti-Myelin Associated Glycoprotein (MAG) (AA 501-582) antibody
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anti-Myelin Associated Glycoprotein (MAG) (C-Term) antibody
MAG 适用: 人, 大鼠 WB, IHC, IP, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

MAG (Myelin Associated Glycoprotein (MAG))

别名

MAG (MAG 产品)

别名

GMA antibody, S-MAG antibody, SIGLEC-4A antibody, SIGLEC4A antibody, siglec-4 antibody, MAG antibody, Gma antibody, siglec-4a antibody, myelin associated glycoprotein antibody, myelin-associated glycoprotein antibody, MAG antibody, mag antibody, Mag antibody

背景

Description: Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury, protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults, this probably depends on binding to gangliosides on the axon cell membrane (By similarity). Negative regulator of neurite outgrowth, in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides. Inhibits axon longitudinal growth (By similarity). Inhibits axon outgrowth by binding to RTN4R (By similarity). Preferentially binds to alpha-2,3-linked sialic acid. Binds ganglioside Gt1b (By similarity).
Gene: MAG

分子量

63 kDa.

基因ID

4099

UniProt

P20916

途径

Neurotrophin Signaling Pathway