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- 抗原 See all LRP4 抗体
- LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRP4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- LRP4 Antibody detects endogenous levels of total LRP4.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human LRP4, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product LRP4 Primary Antibody
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anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 1610-1885) antibody
LRP4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibodyLRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (HRP)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 HRP
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (FITC)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 FITC
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (Biotin)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 Biotin
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (PE)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 PE
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (APC)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 APC
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (PerCP)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 PerCP
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (Atto 488)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 Atto 488
anti-Low Density Lipoprotein Receptor-Related Protein 4 (LRP4) (AA 26-350) antibody (Atto 594)LRP4 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S207-27 Atto 594
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))
- 别名
- LRP4 (LRP4 产品)
- 别名
- CLSS antibody, LRP-4 antibody, LRP10 antibody, MEGF7 antibody, SOST2 antibody, Megf7 antibody, 6430526J12Rik antibody, D230026E03 antibody, mdig antibody, LRP4 antibody, lrp10 antibody, megf7 antibody, LDL receptor related protein 4 antibody, low density lipoprotein receptor-related protein 4 antibody, LRP4 antibody, Lrp4 antibody, lrp4 antibody
- 背景
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Description: Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes. May play an essential role in the process of digit differentiation (By similarity).
Gene: LRP4
- 分子量
- 212kDa
- 基因ID
- 4038
- UniProt
- O75096
- 途径
- Skeletal Muscle Fiber Development
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