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LC3B 抗体 (N-Term)

Name: LC3B 抗体 (N-Term)
SKU: ABIN6262925
Availability: OutOfStock

MAP1LC3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of lc3A/Bexpression in HeLa whole cell lysate. (LC3B 抗体 (N-Term))

ABIN6268948 at 1/100 staining Mouse testis tissue by IHC-P. (LC3B 抗体 (N-Term))

IHC

ABIN6268948 staining lovo cells by ICC/IF. (LC3B 抗体 (N-Term))

IF/ICC

3 images

(4 references)

产品编号 ABIN6262925

发货至: 中国

Datasheet as PDF

抗原 See all LC3B (MAP1LC3B) 抗体

LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
抗原表位
23

15

13

11

9

8

7

7

7

6

5

5

5

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
129

47

32

4

4

4

2

1

1

1

1
人, 小鼠, 大鼠
宿主
119

13

7
兔
Compatible Secondaries
克隆类型
125

15
多克隆
标记
71

14

13

10

10

10

2

2

2

2

2

2
This LC3B antibody is un-conjugated
应用范围
86

55

47

26

20

13

11

8

5

4

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

LC3A/B Antibody detects endogenous levels of total LC3A/B.

预测反应

Pig,Zebrafish,Bovine,Sheep,Dog,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human LC3B, corresponding to a region within N-terminal amino acids.

亚型

IgG

Top Product

Discover our top product MAP1LC3B Primary Antibody
anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) antibody
MAP1LC3B 适用: 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) antibody
KO Validated MAP1LC3B 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) antibody
MAP1LC3B 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) antibody
MAP1LC3B 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) (AA 1-100) antibody
MAP1LC3B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) antibody
MAP1LC3B 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5H12 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) (AA 74-106) antibody
MAP1LC3B 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) (AA 1-30), (N-Term) antibody
MAP1LC3B 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) (AA 89-122), (cleaved) antibody
MAP1LC3B 适用: 人, 小鼠 IF, ICC 宿主: 兔 Polyclonal RB15839-RB28608 unconjugated

anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) (AA 77-106) antibody
MAP1LC3B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Tang, Cui, Luan, Ruan, Wang, Yang, Wang, Liu, Wang: "Human tissue kallikrein 1 ameliorates erectile function via modulation of macroautophagy in aged transgenic rats." in: Andrology, (2018) (PubMed).

Feng, Lu, He, Wang, Qi, Pi, Zhang: "Mycobacterium smegmatis Induces Neurite Outgrowth and Differentiation in an Autophagy-Independent Manner in PC12 and C17.2 Cells." in: Frontiers in cellular and infection microbiology, Vol. 8, pp. 201, (2018) (PubMed).

Shao, Yang, Xu, Zhu, Huang, Li, Wu, Yue, Xiong, Chen, Kuang, Fan, Zhu, Zeng: "Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells." in: Stem cell research & therapy, Vol. 9, Issue 1, pp. 219, (2018) (PubMed).

Wu, Zheng, Bai, Xia, Zhang, Guo: "HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma." in: OncoTargets and therapy, Vol. 11, pp. 4501-4510, (2018) (PubMed).
抗原

LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))

别名

MAP1LC3A,MAP1LC3B (MAP1LC3B 产品)

别名

ATG8F antibody, LC3B antibody, MAP1A/1BLC3 antibody, MAP1LC3B-a antibody, Map1lc3 antibody, Mpl3 antibody, zbs559 antibody, 1010001C15Rik antibody, Atg8 antibody, LC3b antibody, zgc:56434 antibody, wu:fb60g11 antibody, map1lc3b antibody, MGC76283 antibody, MAP1LC3B antibody, microtubule associated protein 1 light chain 3 beta antibody, microtubule-associated protein 1 light chain 3 beta antibody, microtubule associated protein 1 light chain 3 beta L homeolog antibody, MAP1LC3B antibody, Map1lc3b antibody, map1lc3b antibody, map1lc3b.L antibody

背景

Description: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Gene: MAP1LC3B

分子量

14.16 kDa

基因ID

84557, 81631

UniProt

Q9H492, Q9GZQ8

途径

Autophagy