KIR2DS5 抗体 (Internal Region)
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- 抗原 See all KIR2DS5 products
- KIR2DS5 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 5 (KIR2DS5))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIR2DS5 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- KIR2DS5 Antibody detects endogenous levels of total KIR2DS5.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human KIR2DS5, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- KIR2DS5 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 5 (KIR2DS5))
- 别名
- KIR2DS5 (KIR2DS5 产品)
- 别名
- CD158G antibody, NKAT9 antibody, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5 antibody, KIR2DS5 antibody
- 背景
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Description: Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity (PubMed:28685972, PubMed:18624290, PubMed:18682925). Able to activate NK cells citotoxicity and cytokine production such as IFNG (PubMed:18624290, PubMed:24269691). Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 reprensented in this entry (PubMed:28685972).
Gene: KIR2DS5
- 分子量
- 34 kDa
- 基因ID
- 3810
- UniProt
- Q14953
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