KIDINS220 抗体 (Internal Region)
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- 抗原 See all KIDINS220 抗体
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
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抗原表位
- Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KIDINS220 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- KIDINS220 Antibody detects endogenous levels of total KIDINS220.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human KIDINS220, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (C-Term) antibody
KIDINS220 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (pSer918) antibodyKIDINS220 适用: 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Kinase D-Interacting Substrate, 220kDa (KIDINS220) (AA 1335-1348), (C-Term), (Intracellular) antibodyKIDINS220 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- KIDINS220 (Kinase D-Interacting Substrate, 220kDa (KIDINS220))
- 别名
- KIDINS220 (KIDINS220 产品)
- 别名
- ARMS antibody, fj35h03 antibody, kidins220 antibody, zgc:63531 antibody, dZ119J18.2 antibody, wu:fj35h03 antibody, 3110039L19Rik antibody, AI194387 antibody, AI316525 antibody, C330002I19Rik antibody, mKIAA1250 antibody, kinase D interacting substrate 220 antibody, kinase D-interacting substrate 220 antibody, kinase D-interacting substrate 220b antibody, kinase D-interacting substrate 220kDa antibody, KIDINS220 antibody, Kidins220 antibody, kidins220b antibody
- 背景
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Description: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.
Gene: KIDINS220
- 分子量
- 186-197 kDa
- 基因ID
- 57498
- UniProt
- Q9ULH0
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