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- 抗原 See all KDM5A 抗体
- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDM5A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- KDM5A Antibody detects endogenous levels of total KDM5A.
- 预测反应
- Pig,Horse,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human KDM5A, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product KDM5A Primary Antibody
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anti-Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 1416-1434) antibody
KDM5A 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 18E8 unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) antibodyKDM5A 适用: 人 WB, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 191-290) antibodyKDM5A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) antibodyKDM5A 适用: 人 WB, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 101-200) antibodyKDM5A 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 437-603) antibodyKDM5A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 191-290) antibodyKDM5A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) antibodyKDM5A 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 1609-1641), (C-Term) antibodyKDM5A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB10761 unconjugated
anti-Lysine (K)-Specific Demethylase 5A (KDM5A) (AA 1608-1641), (C-Term) antibodyKDM5A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
- 别名
- KDM5A (KDM5A 产品)
- 别名
- Jarid1a antibody, JARID1A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, AA409370 antibody, C76986 antibody, Rbbp2 antibody, lysine demethylase 5A antibody, lysine (K)-specific demethylase 5A antibody, Kdm5a antibody, KDM5A antibody
- 背景
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Description: Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Regulates specific gene transcription through DNA-binding on 5'-CCGCCC-3' motif (PubMed:18270511). May stimulate transcription mediated by nuclear receptors. Involved in transcriptional regulation of Hox proteins during cell differentiation (PubMed:19430464). May participate in transcriptional repression of cytokines such as CXCL12. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. In a histone demethylase-independent manner, acts as a coactivator of the CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER1/2 and other clock-controlled genes and increases histone acetylation at PER1/2 promoters by inhibiting the activity of HDAC1 (By similarity). Seems to act as a transcriptional corepressor for some genes such as MT1F and to favor the proliferation of cancer cells (PubMed:27427228).
Gene: KDM5A
- 分子量
- 192kDa
- 基因ID
- 5927
- UniProt
- P29375
- 途径
- Chromatin Binding, Warburg Effect
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