KCNMB3 抗体 (N-Term)
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- 抗原 See all KCNMB3 抗体
- KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNMB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- KCNMB3 Antibody detects endogenous levels of total KCNMB3.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human KCNMB3, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product KCNMB3 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- KCNMB3 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M beta Member 3 (KCNMB3))
- 别名
- KCNMB3 (KCNMB3 产品)
- 别名
- KCNMB3 antibody, BKBETA3 antibody, HBETA3 antibody, KCNMB2 antibody, KCNMBL antibody, SLOBETA3 antibody, EG435726 antibody, Gm5707 antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 3 antibody, potassium channel subfamily M regulatory beta subunit 3 S homeolog antibody, potassium large conductance calcium-activated channel, subfamily M beta member 3 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 3 antibody, KCNMB3 antibody, kcnmb3.S antibody, Kcnmb3 antibody
- 背景
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Description: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 partially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer.
Gene: KCNMB3
- 分子量
- 32 kDa
- 基因ID
- 27094
- UniProt
- Q9NPA1
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