电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

IRG1 抗体 (C-Term)

IRG1 适用: 人 ELISA, WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262659
发货至: 中国
  • 抗原 See all IRG1 products
    IRG1 (Immunoresponsive Gene 1 (IRG1))
    抗原表位
    C-Term
    适用
    • 12
    • 1
    宿主
    • 12
    克隆类型
    • 12
    多克隆
    标记
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRG1 antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    特异性
    IRG1 Antibody detects endogenous levels of total IRG1.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IRG1, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    IRG1 (Immunoresponsive Gene 1 (IRG1))
    别名
    ACOD1 (IRG1 产品)
    别名
    CAD antibody, AI323667 antibody, aconitate decarboxylase 1 antibody, ACOD1 antibody, Acod1 antibody
    背景

    Description: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

    Gene: ACOD1

    分子量
    55 kDa
    基因ID
    730249
    UniProt
    A6NK06
You are here:
客服