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- 抗原 See all IRG1 products
- IRG1 (Immunoresponsive Gene 1 (IRG1))
- 抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRG1 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- IRG1 Antibody detects endogenous levels of total IRG1.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human IRG1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
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anti-Immunoresponsive Gene 1 (IRG1) (AA 57-257) antibody
IRG1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Immunoresponsive Gene 1 (IRG1) antibodyIRG1 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- IRG1 (Immunoresponsive Gene 1 (IRG1))
- 别名
- ACOD1 (IRG1 产品)
- 别名
- CAD antibody, AI323667 antibody, aconitate decarboxylase 1 antibody, ACOD1 antibody, Acod1 antibody
- 背景
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Description: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
Gene: ACOD1
- 分子量
- 55 kDa
- 基因ID
- 730249
- UniProt
- A6NK06
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